Extrahepatic metabolism of zidovudine.
نویسندگان
چکیده
منابع مشابه
Intracellular metabolism of zidovudine and stavudine in combination.
To the Editor-We read with interest the findings of Merrill et at. [1] that for zidovudine-resistant isolates of human immunodefi-ciency virus type 1 (HIV-1), the addition of zidovudine to stavu-dine antagonized the antiviral effect of stavudine in vitro as judged by inhibition of p24 antigen production. The combination of the two drugs was, however, synergistic against zidovudine-sensitive str...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1992
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1992.tb04024.x